The 18th eChallenges e-2008 Conference takes place 22-24 October 2008 in Stockholm (Sweden). The annual conference aims at sharing knowledge and experience, lessons learnt and good practice in the areas of ICT for Networked Enterprise & RFID, eGovernment & eDemocracy, eHealth, Collaborative Working Environments, Technology Enhanced Learning and ICT Skills, Knowledge and Content Technologies, Security and Identity Management, GRID and Mobility.